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RTN4R

Description reticulon 4 receptor
Image
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Cell Surface
  • Anchored Component Of External Side Of Plasma Membrane
  • Neuron Projection
  • Neuronal Cell Body
  • Dendritic Shaft
  • Perikaryon
  • Axonal Growth Cone
  • Membrane Raft
  • Extracellular Exosome
  • Presynapse
  • Glutamatergic Synapse
Molecular Function
  • Protein Binding
  • Heparin Binding
  • Chondroitin Sulfate Binding
  • Signaling Receptor Activity
  • Neuregulin Receptor Activity
  • Protein-containing Complex Binding
  • Ganglioside GM1 Binding
  • Ganglioside GT1b Binding
Biological Process
  • Cell Surface Receptor Signaling Pathway
  • Axonogenesis
  • Negative Regulation Of Neuron Projection Development
  • Corpus Callosum Development
  • Neuronal Signal Transduction
  • Negative Regulation Of Axon Extension
  • Positive Regulation Of Rho Protein Signal Transduction
  • Positive Regulation Of GTPase Activity
  • Negative Regulation Of Axon Regeneration
Pathways
  • Axonal growth inhibition (RHOA activation)
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576 29875488)
  • Obesity-related traits ( 23251661)
Interacting Genes 13 interacting genes: HOXA1 KEAP1 LINGO1 MAG MGAT5B NEK1 NGFR OMG OTX1 PTK7 RTN4 RTN4IP1 ZDHHC8
Entrez ID 65078
HPRD ID 16123
Ensembl ID ENSG00000040608
Uniprot IDs Q9BZR6
PDB IDs 1OZN 1P8T
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025