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CENPH

Description centromere protein H
Image No pdb structure
GO Annotations Cellular Component
  • Kinetochore
  • Nucleus
  • Nucleoplasm
  • Chromosome
  • Nucleolus
  • Cytosol
Molecular Function
  • Protein Binding
  • Kinetochore Binding
Biological Process
  • Mitotic Spindle Organization
  • Chromosome Segregation
  • Kinetochore Assembly
  • Kinetochore Organization
Pathways
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • RHO GTPases Activate Formins
  • Deposition of new CENPA-containing nucleosomes at the centromere
  • Mitotic Prometaphase
  • EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Interacting Genes 18 interacting genes: ABI2 C1orf216 C8orf58 CCDC146 DCTN2 ERH H2AP KIF2C LMNB1 MESD MTAP NDC80 NUF2 NUP54 RASSF4 SPAG5 ZNF493 ZSCAN12
Entrez ID 64946
HPRD ID 12029
Ensembl ID ENSG00000153044
Uniprot IDs A0A0S2Z5T0 Q9H3R5
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025