SALL1

Description		spalt like transcription factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Heterochromatin Nucleus Nucleoplasm Cytoplasm Chromocenter
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Beta-catenin Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Ureteric Bud Development Branching Involved In Ureteric Bud Morphogenesis Kidney Development Ventricular Septum Development Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Regulation Of Transcription By RNA Polymerase II Heart Development Gonad Development Olfactory Nerve Development Olfactory Bulb Interneuron Differentiation Pituitary Gland Development Positive Regulation Of Wnt Signaling Pathway Adrenal Gland Development Inductive Cell-cell Signaling Embryonic Digit Morphogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Digestive Tract Development Limb Development Olfactory Bulb Mitral Cell Layer Development Kidney Epithelium Development Ureteric Bud Invasion
Pathways		POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Age-related cognitive decline (visuospatial skill) (slope of z-scores) ( 30954325) Blood pressure measurement (high sodium and potassium intervention) ( 24165912) Body size at age 10 ( 32376654) C-reactive protein levels ( 30388399 21300955) Cortical thickness ( 32963231) Creatinine levels ( 29403010) Dentures ( 31235808) Diabetes mellitus ( 29615537) Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Essential hypertension (time to event) ( 32589924) Estimated glomerular filtration rate ( 31015462 30604766) Facial morphology ( 31763980) Femoral neck bone mineral density ( 22504420) Glaucoma (primary open-angle) ( 33627673) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Left superior temporal gyrus thickness (schizophrenia interaction) ( 26249676) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Optic cup area ( 25631615 31798171 28073927) Optic disc area ( 25631615 31798171 28073927) Optic disc parameters ( 20548946) Optic disc size ( 31809533) Pelvic organ prolapse ( 32184442) Red blood cell count ( 32888494) Serum metabolite levels ( 33031748) Uterine fibroids ( 30194396) Vertical cup-disc ratio ( 31798171 25241763) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Weight loss (gastric bypass surgery) ( 23643386) White matter hyperintensity volume ( 33293549) White matter hyperintensity volume (adjusted for hypertension) ( 33293549) White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
Interacting Genes		8 interacting genes: CRBN CTNNB1 HDAC1 HDAC2 PPP1R13B SUMO1 TERF1 UBE2I
Entrez ID		6299
HPRD ID		03742
Ensembl ID		ENSG00000103449
Uniprot IDs		Q9NSC2
PDB IDs
Enriched GO Terms of Interacting Partners?
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