S100A9

Description		S100 calcium binding protein A9
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell Junction Secretory Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Microtubule Binding Zinc Ion Binding Antioxidant Activity Toll-like Receptor 4 Binding Calcium-dependent Protein Binding Arachidonic Acid Binding RAGE Receptor Binding
	Biological Process	Leukocyte Migration Involved In Inflammatory Response Chronic Inflammatory Response Autophagy Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Inflammatory Response Cell-cell Signaling Positive Regulation Of Neuron Projection Development Astrocyte Development Peptidyl-cysteine S-nitrosylation Positive Regulation Of Cell Growth Neutrophil Chemotaxis Sequestering Of Zinc Ion Response To Lipopolysaccharide Autocrine Signaling Peptidyl-cysteine S-trans-nitrosylation Modulation Of Process Of Other Organism Defense Response To Bacterium Innate Immune Response Regulation Of Integrin Biosynthetic Process Positive Regulation Of Inflammatory Response Defense Response To Fungus Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cytoskeleton Organization Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Neutrophil Aggregation Cellular Oxidant Detoxification Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		ER-Phagosome pathway MyD88:MAL(TIRAP) cascade initiated on plasma membrane MyD88 deficiency (TLR2/4) IRAK4 deficiency (TLR2/4) RHO GTPases Activate NADPH Oxidases Regulation of TLR by endogenous ligand Neutrophil degranulation Metal sequestration by antimicrobial proteins
Drugs		Calcium Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Asthma ( 31619474) Basophil percentage of white cells ( 32888494) Matrix metalloproteinase-8 levels ( 29212897)
Interacting Genes		13 interacting genes: CDC42 EGFR MAGEA1 MAGEA3 MAGEA6 MAPK14 NCF2 PTEN S100A8 S100B TUBA1A TUBB USP13
Entrez ID		6280
HPRD ID		00472
Ensembl ID		ENSG00000163220
Uniprot IDs		P06702
PDB IDs		1IRJ 1XK4 4GGF 4XJK 5I8N 5W1F 6DS2
Enriched GO Terms of Interacting Partners?
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