SALL4

Description		spalt like transcription factor 4
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GO Annotations	Cellular Component	Heterochromatin Nucleus Nucleoplasm Cytoplasm Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Inner Cell Mass Cell Proliferation Neural Tube Closure Ventricular Septum Development Regulation Of Transcription By RNA Polymerase II Stem Cell Population Maintenance Embryonic Limb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II
Pathways		POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Transcriptional regulation of pluripotent stem cells Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases
GWAS		Male infertility ( 19478329) Neuroblastoma (pediatric) ( 32599975) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		2 interacting genes: CRBN RBBP4
Entrez ID		57167
HPRD ID		08458
Ensembl ID		ENSG00000101115
Uniprot IDs		Q9UJQ4
PDB IDs		5XWR 6UML 7BQU 7BQV
Enriched GO Terms of Interacting Partners?
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