NEIL3

Description		nei like DNA glycosylase 3
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome
	Molecular Function	Bubble DNA Binding Damaged DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity Zinc Ion Binding DNA N-glycosylase Activity Class I DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity MCM Complex Binding
	Biological Process	Base-excision Repair Base-excision Repair, AP Site Formation Interstrand Cross-link Repair Depurination
Pathways		Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Recognition and association of DNA glycosylase with site containing an affected purine Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Cleavage of the damaged purine Defective Base Excision Repair Associated with NEIL3 NEIL3-mediated resolution of ICLs NEIL3-mediated resolution of ICLs
Drugs
Diseases
GWAS		Heart rate variability traits ( 17903306) Idiopathic dilated cardiomyopathy ( 29495422) Mastocytosis (KIT D816V positive) ( 33421400) Metabolite levels ( 23823483)
Interacting Genes		2 interacting genes: TP53 TWIST1
Entrez ID		55247
HPRD ID		16407
Ensembl ID		ENSG00000109674
Uniprot IDs		Q8TAT5
PDB IDs		7JL5
Enriched GO Terms of Interacting Partners?
Tagcloud ?