INO80

Description		INO80 complex ATPase subunit
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spindle Cytosol Microtubule Nuclear Body Ino80 Complex
	Molecular Function	DNA Binding Actin Binding Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA ATP Hydrolysis Activity Histone Binding Alpha-tubulin Binding ATP-dependent Chromatin Remodeler Activity
	Biological Process	Mitotic Sister Chromatid Segregation Double-strand Break Repair Via Homologous Recombination DNA Repair Double-strand Break Repair Chromatin Remodeling Transcription, DNA-templated Positive Regulation Of Nuclear Cell Cycle DNA Replication Positive Regulation Of Cell Growth Cellular Response To UV Nucleosome Mobilization Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Transcription By RNA Polymerase II Spindle Assembly Cell Division UV-damage Excision Repair Cellular Response To Ionizing Radiation Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		UCH proteinases DNA Damage Recognition in GG-NER
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Diastolic blood pressure ( 27841878) Estimated glomerular filtration rate ( 31152163 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Frailty index ( 34431594) Glomerular filtration rate (creatinine) ( 28452372 26831199) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Macular thickness ( 30535121) Malaria ( 31844061) Menopause (age at onset) ( 26414677) Offspring birth weight ( 31043758) Pulse pressure ( 27841878) Red blood cell count ( 32888494) Systolic blood pressure ( 27841878) Ulcerative colitis ( 28067908)
Interacting Genes		2 interacting genes: ACTN4 PLEKHF2
Entrez ID		54617
HPRD ID		10024
Ensembl ID		ENSG00000128908
Uniprot IDs		A0A024R9R7 Q9ULG1
PDB IDs		6HTS
Enriched GO Terms of Interacting Partners?
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