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LCMT1

Description leucine carboxyl methyltransferase 1
Image
GO Annotations Cellular Component
  • Nucleoplasm
  • Cytosol
Molecular Function
  • Protein C-terminal Carboxyl O-methyltransferase Activity
  • Protein Binding
  • S-adenosylmethionine-dependent Methyltransferase Activity
  • Protein C-terminal Leucine Carboxyl O-methyltransferase Activity
Biological Process
  • G2/M Transition Of Mitotic Cell Cycle
  • Cellular Protein Modification Process
  • Protein Methylation
  • C-terminal Protein Methylation
  • Regulation Of Glucose Metabolic Process
  • Negative Regulation Of Protein-containing Complex Assembly
  • Regulation Of Apoptotic Process
  • Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Pathways
  • Cyclin A/B1/B2 associated events during G2/M transition
Drugs
  • Leucine
Diseases
GWAS
  • Cleft palate ( 28054174)
  • Lead levels ( 26025379)
Interacting Genes 4 interacting genes: BRCA1 FXR2 PPP2CB TAB1
Entrez ID 51451
HPRD ID 17266
Ensembl ID ENSG00000205629
Uniprot IDs Q9UIC8
PDB IDs 3IEI 3O7W 3P71
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025