MBTPS2

Description		membrane bound transcription factor peptidase, site 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Integral Component Of Membrane
	Molecular Function	Metalloendopeptidase Activity Metal Ion Binding
	Biological Process	Cholesterol Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Membrane Protein Intracellular Domain Proteolysis Response To Endoplasmic Reticulum Stress ATF6-mediated Unfolded Protein Response Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of DNA-binding Transcription Factor Activity Bone Maturation Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) ATF6 (ATF6-alpha) activates chaperones CREB3 factors activate genes CREB3 factors activate genes Assembly of active LPL and LIPC lipase complexes
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: ATF6B BDNF
Entrez ID		51360
HPRD ID		02243
Ensembl ID		ENSG00000012174
Uniprot IDs		O43462
PDB IDs
Enriched GO Terms of Interacting Partners?
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