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PDCD1

Description programmed cell death 1
Image
GO Annotations Cellular Component
  • Plasma Membrane
  • External Side Of Plasma Membrane
  • Integral Component Of Membrane
Molecular Function
  • Protein Binding
Biological Process
  • Adaptive Immune Response
  • Apoptotic Process
  • Humoral Immune Response
  • Multicellular Organism Development
  • Regulation Of Immune Response
  • Negative Regulation Of Immune Response
  • Positive Regulation Of T Cell Apoptotic Process
Pathways
  • PD-1 signaling
  • Potential therapeutics for SARS
Drugs
  • CT-011
  • Nivolumab
  • Pembrolizumab
  • Cemiplimab
  • Camrelizumab
  • Spartalizumab
  • Tislelizumab
  • Toripalimab
  • Dostarlimab
  • Sintilimab
  • Retifanlimab
  • AMP-224
  • MEDI0680
Diseases
GWAS
  • Crohn's disease ( 26192919)
  • Eosinophil counts ( 32888494)
  • Eosinophil percentage of white cells ( 32888494)
Interacting Genes 5 interacting genes: CD274 COPS8 MCL1 OR6B3 PDCD1LG2
Entrez ID 5133
HPRD ID 02590
Ensembl ID ENSG00000188389
Uniprot IDs A0A0M3M0G7 Q15116
PDB IDs 2M2D 3RRQ 4ZQK 5B8C 5GGR 5GGS 5IUS 5JXE 5WT9 6HIG 6J14 6J15 6JBT 6JJP 6K0Y 6R5G 6ROY 6ROZ 6UMT 6UMU 6UMV 6XKR 7BXA 7CU5
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025