OPHN1

Description		oligophrenin 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Actin Cytoskeleton Terminal Bouton Dendritic Spine Glutamatergic Synapse
	Molecular Function	Actin Binding GTPase Activator Activity Phospholipid Binding Ionotropic Glutamate Receptor Binding
	Biological Process	Substrate-dependent Cell Migration, Cell Extension Signal Transduction Nervous System Development Axon Guidance Cerebellar Granule Cell Differentiation Cerebral Cortex Neuron Differentiation Actin Cytoskeleton Organization Regulation Of Endocytosis Neuron Differentiation Neuron Projection Development Cell Junction Assembly Regulation Of Rho Protein Signal Transduction Establishment Of Epithelial Cell Apical/basal Polarity Synaptic Vesicle Endocytosis Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Catalytic Activity Regulation Of Synaptic Transmission, Glutamatergic Maintenance Of Postsynaptic Specialization Structure Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Negative Regulation Of Proteasomal Protein Catabolic Process
Pathways		RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS		Excessive daytime sleepiness ( 27992416) Male-pattern baldness ( 30573740 28196072)
Interacting Genes		3 interacting genes: CDC42 RAC1 RHOA
Entrez ID		4983
HPRD ID		02130
Ensembl ID		ENSG00000079482
Uniprot IDs		O60890
PDB IDs
Enriched GO Terms of Interacting Partners?
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