NQO2

Description		N-ribosyldihydronicotinamide:quinone reductase 2
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	Dihydronicotinamide Riboside Quinone Reductase Activity NAD(P)H Dehydrogenase (quinone) Activity Protein Binding Zinc Ion Binding Electron Transfer Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Other Nitrogenous Compounds As Donors Chloride Ion Binding Protein Homodimerization Activity FAD Binding Melatonin Binding Resveratrol Binding
	Biological Process	Memory Electron Transport Chain Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of ERK1 And ERK2 Cascade Quinone Catabolic Process Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Phase I - Functionalization of compounds
Drugs		NADH Menadione Melatonin Primaquine Resveratrol Flavin adenine dinucleotide 10-Propargyl-5,8-Dideazafolic Acid Quercetin Tretazicar (3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide 5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one Casimiroin
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		10 interacting genes: CSF3 DDIT4L DGCR6 DRD2 EFHC1 GORASP2 IL32 LRRC7 MTCH1 SPG21
Entrez ID		4835
HPRD ID		01190
Ensembl ID		ENSG00000124588
Uniprot IDs		B3KPX6 P16083 Q5TD07
PDB IDs		1QR2 1SG0 1XI2 1ZX1 2BZS 2QMY 2QMZ 2QR2 2QWX 2QX4 2QX6 2QX8 2QX9 3FW1 3G5M 3GAM 3NFR 3NHF 3NHJ 3NHK 3NHL 3NHP 3NHR 3NHS 3NHU 3NHW 3NHY 3O2N 3O73 3OVM 3OWH 3OWX 3OX1 3OX2 3OX3 3TE7 3TEM 3TZB 3UXE 3UXH 4FGJ 4FGK 4FGL 4GQI 4GR9 4QOD 4QOE 4QOF 4QOG 4QOH 4QOI 4QOJ 4U7F 4U7G 4U7H 4XDG 4XDH 4ZVK 4ZVL 4ZVM 4ZVN 5BUC 5LBT 5LBU 5LBW 5LBY 5LBZ
Enriched GO Terms of Interacting Partners?
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