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ASNS

Description asparagine synthetase (glutamine-hydrolyzing)
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GO Annotations Cellular Component
  • Cytosol
Molecular Function
  • Asparagine Synthase (glutamine-hydrolyzing) Activity
  • Protein Binding
  • ATP Binding
  • Identical Protein Binding
Biological Process
  • Liver Development
  • Asparagine Biosynthetic Process
  • Glutamine Metabolic Process
  • Response To Light Stimulus
  • Response To Mechanical Stimulus
  • Response To Toxic Substance
  • Response To Methotrexate
  • Response To Follicle-stimulating Hormone
  • Cellular Response To Hormone Stimulus
  • Cellular Response To Glucose Starvation
  • Negative Regulation Of Apoptotic Process
  • Response To Amino Acid
  • Positive Regulation Of Mitotic Cell Cycle
  • L-asparagine Biosynthetic Process
Pathways
  • ATF4 activates genes in response to endoplasmic reticulum stress
  • Aspartate and asparagine metabolism
  • Response of EIF2AK4 (GCN2) to amino acid deficiency
  • Response of EIF2AK1 (HRI) to heme deficiency
Drugs
  • Aspartic acid
  • Glutamic acid
  • ATP
  • Asparagine
Diseases
GWAS
  • Regular attendance at a religious group ( 29970889)
  • Tuberculosis ( 30713548)
Interacting Genes 6 interacting genes: ATXN1 RAB8A STRN4 SUMO2 TRIM69 WDR27
Entrez ID 440
HPRD ID 00153
Ensembl ID ENSG00000070669
Uniprot IDs P08243
PDB IDs 6GQ3
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025