ME1

Description		malic enzyme 1
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GO Annotations	Cellular Component	Mitochondrion Cytosol
	Molecular Function	Malic Enzyme Activity Malate Dehydrogenase (decarboxylating) (NAD+) Activity Malate Dehydrogenase (decarboxylating) (NADP+) Activity Oxaloacetate Decarboxylase Activity Electron Transfer Activity Manganese Ion Binding Identical Protein Binding ADP Binding NADP Binding NAD Binding
	Biological Process	Carbohydrate Metabolic Process Pyruvate Metabolic Process Malate Metabolic Process Nucleotide Biosynthetic Process Response To Hormone Response To Carbohydrate Electron Transport Chain Regulation Of NADP Metabolic Process
Pathways		PPARA activates gene expression Pyruvate metabolism
Drugs		NADH Nicotinamide adenine dinucleotide phosphate
Diseases
GWAS		Bipolar disorder ( 33169155) Birth weight ( 31043758) Serum polyunsaturated fatty acid concentration x Mediterranean diet adherence interaction in metabolic syndrome ( 31991592)
Interacting Genes		2 interacting genes: AP1B1 OGT
Entrez ID		4199
HPRD ID		01102
Ensembl ID		ENSG00000065833
Uniprot IDs		P48163
PDB IDs		2AW5 3WJA
Enriched GO Terms of Interacting Partners?
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