MCM4

Description		minichromosome maintenance complex component 4
Image
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Membrane MCM Complex CMG Complex
	Molecular Function	DNA Helicase Activity Single-stranded DNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity Single-stranded DNA Helicase Activity
	Biological Process	Double-strand Break Repair Via Break-induced Replication DNA Replication DNA Unwinding Involved In DNA Replication DNA Strand Elongation Involved In DNA Replication Mitotic DNA Replication Initiation
Pathways		Activation of ATR in response to replication stress Unwinding of DNA Assembly of the pre-replicative complex Orc1 removal from chromatin Activation of the pre-replicative complex Switching of origins to a post-replicative state
Drugs
Diseases
GWAS		Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 27863252) Reticulocyte count ( 32888494)
Interacting Genes		27 interacting genes: CCNA1 CDC5L CDC7 CDK1 CDK2 CDT1 DBF4 EP300 ESCO2 LIG4 MCM2 MCM3 MCM6 MCM7 MCM8 MCMBP ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 RPA1 SSRP1 SUMO2 SUPT16H TLX2
Entrez ID		4173
HPRD ID		09094
Ensembl ID		ENSG00000104738
Uniprot IDs		B3KMX0 B4DLA6 P33991
PDB IDs		6XTX 6XTY
Enriched GO Terms of Interacting Partners?
Tagcloud ?