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ARG2

Description arginase 2
Image
GO Annotations Cellular Component
  • Cytoplasm
  • Mitochondrion
  • Mitochondrial Matrix
Molecular Function
  • Arginase Activity
  • Protein Binding
  • Manganese Ion Binding
Biological Process
  • Urea Cycle
  • Ureteric Bud Development
  • Adaptive Immune Response
  • Negative Regulation Of Type 2 Immune Response
  • Nitric Oxide Biosynthetic Process
  • Striated Muscle Contraction
  • Arginine Catabolic Process To Ornithine
  • Regulation Of Interleukin-1 Beta Production
  • Negative Regulation Of Interleukin-13 Production
  • Negative Regulation Of Interleukin-17 Production
  • Negative Regulation Of Tumor Necrosis Factor Production
  • Innate Immune Response
  • Negative Regulation Of Macrophage Inflammatory Protein 1 Alpha Production
  • Negative Regulation Of Chemokine (C-C Motif) Ligand 4 Production
  • Negative Regulation Of Chemokine (C-C Motif) Ligand 5 Production
  • Negative Regulation Of Defense Response To Bacterium
  • Regulation Of Reactive Oxygen Species Biosynthetic Process
  • Negative Regulation Of Activated CD8-positive, Alpha-beta T Cell Apoptotic Process
  • Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
  • Positive Regulation Of Cellular Senescence
Pathways
  • Urea cycle
Drugs
  • Arginine
  • Ornithine
  • S-2-(Boronoethyl)-L-Cysteine
Diseases
GWAS
Interacting Genes 3 interacting genes: ARG1 DCC STK11
Entrez ID 384
HPRD ID 00143
Ensembl ID ENSG00000081181
Uniprot IDs A0A024R6A0 P78540
PDB IDs 1PQ3 4HZE 4I06 4IE2 4IE3 4IXU 4IXV 6Q37 6Q39 6SS2 6SS4 6SS6
Enriched GO Terms of Interacting Partners?
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