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KIF5A

Description kinesin family member 5A
Image
GO Annotations Cellular Component
  • Cytosol
  • Kinesin Complex
  • Microtubule
  • Membrane
  • Dendrite Cytoplasm
  • Ciliary Rootlet
  • Perikaryon
  • Synapse
  • Perinuclear Region Of Cytoplasm
  • Axon Cytoplasm
Molecular Function
  • Cytoskeletal Motor Activity
  • Microtubule Motor Activity
  • Protein Binding
  • ATP Binding
  • Microtubule Binding
  • Plus-end-directed Microtubule Motor Activity
  • ATP Hydrolysis Activity
  • Kinesin Binding
Biological Process
  • Microtubule-based Movement
  • Chemical Synaptic Transmission
  • Axon Guidance
  • Vesicle-mediated Transport
  • Cytoskeleton-dependent Intracellular Transport
  • Synaptic Vesicle Transport
  • Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex
  • Anterograde Axonal Protein Transport
  • Retrograde Neuronal Dense Core Vesicle Transport
Pathways
  • MHC class II antigen presentation
  • Insulin processing
  • RHO GTPases activate KTN1
  • COPI-dependent Golgi-to-ER retrograde traffic
  • Kinesins
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis ( 29566793)
  • Rheumatoid arthritis ( 24449572 18794853)
  • Smoking initiation (ever regular vs never regular) ( 30679032)
Interacting Genes 21 interacting genes: CREBBP DTNB ITSN1 KCNE3 KIF5B KIF5C KLC3 MAP4K4 MAPK10 NCOA2 NDEL1 PIN1 RAPGEF2 SMN1 TK1 TP53BP2 TRIM55 TRIM63 TSC1 TSG101 YAP1
Entrez ID 3798
HPRD ID 09108
Ensembl ID ENSG00000155980
Uniprot IDs Q12840
PDB IDs 4UXT 4UXY 4UY0
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025