IL11

Description		interleukin 11
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Cytokine Activity Interleukin-11 Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Signal Transduction Positive Regulation Of Cell Population Proliferation B Cell Differentiation Megakaryocyte Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of MAPK Cascade Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Hormone Secretion Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Complement-dependent Cytotoxicity Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways		IL-6-type cytokine receptor ligand interactions
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Osteoarthritis (hip) ( 30374069) Response to antidepressants ( 20360315)
Interacting Genes		3 interacting genes: IL11RA MAGEA11 UBQLN2
Entrez ID		3589
HPRD ID		00980
Ensembl ID		ENSG00000095752
Uniprot IDs		A8K3F7 P20809
PDB IDs		4MHL 6O4O
Enriched GO Terms of Interacting Partners?
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