HMGCS1

Description		3-hydroxy-3-methylglutaryl-CoA synthase 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Hydroxymethylglutaryl-CoA Synthase Activity Isomerase Activity Protein Homodimerization Activity Organic Acid Binding
	Biological Process	Liver Development Acetyl-CoA Metabolic Process Lipid Metabolic Process Cholesterol Biosynthetic Process Brain Development Male Gonad Development Response To Xenobiotic Stimulus Response To Low Light Intensity Stimulus Farnesyl Diphosphate Biosynthetic Process, Mevalonate Pathway Response To Purine-containing Compound Response To Vitamin E Response To Tellurium Ion Cellular Response To Follicle-stimulating Hormone Stimulus Cellular Response To Cholesterol Cellular Response To Low-density Lipoprotein Particle Stimulus
Pathways		Cholesterol biosynthesis PPARA activates gene expression Activation of gene expression by SREBF (SREBP)
Drugs		(7R,12R,13R)-13-formyl-12,14-dihydroxy-3,5,7-trimethyltetradeca-2,4-dienoic acid
Diseases
GWAS
Interacting Genes		2 interacting genes: OGT SPOP
Entrez ID		3157
HPRD ID		07515
Ensembl ID		ENSG00000112972
Uniprot IDs		A0A024R059 Q01581
PDB IDs		2P8U
Enriched GO Terms of Interacting Partners?
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