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NOP53
Description
NOP53 ribosome biogenesis factor
Image
No pdb structure
GO Annotations
Cellular Component
Fibrillar Center
Nucleoplasm
Nucleolus
Cytosol
RDNA Heterochromatin
Intracellular Membrane-bounded Organelle
Molecular Function
P53 Binding
RNA Binding
Protein Binding
5S RRNA Binding
Identical Protein Binding
Biological Process
Ribosomal Large Subunit Assembly
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Protein Phosphorylation
DNA Repair
RRNA Processing
Cellular Response To DNA Damage Stimulus
Mitotic G2 DNA Damage Checkpoint Signaling
Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Negative Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of RIG-I Signaling Pathway
Regulation Of Apoptotic Process
Protein Stabilization
Regulation Of Cell Cycle
Negative Regulation Of Protein Kinase B Signaling
Cellular Response To Hypoxia
Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Protein Localization To Nucleolus
Positive Regulation Of Protein K63-linked Deubiquitination
Regulation Of Aerobic Respiration
Protein Localization To Nucleoplasm
Pathways
Drugs
Diseases
GWAS
Interacting Genes
14 interacting genes:
CCDC136
CDKN2A
CEP70
HAP1
HMGB2
MDM2
OGT
PPP1CA
PSMA1
SPTBN1
SRPK2
TP53
TSPYL2
UPF2
Entrez ID
29997
HPRD ID
16142
Ensembl ID
ENSG00000105373
Uniprot IDs
Q9NZM5
PDB IDs
Enriched GO Terms of Interacting Partners
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