HiPPIP
  • Home
  • About
  • SZ Genes
  • People
  • Help
  • Advanced Search

BLNK

Description B cell linker
Image No pdb structure
GO Annotations Cellular Component
  • Cytoplasm
  • Cytosol
  • Plasma Membrane
  • Membrane
  • Cytoplasmic Ribonucleoprotein Granule
Molecular Function
  • Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity
  • Protein Binding
  • Enzyme Binding
  • Protein Kinase Binding
  • Signaling Adaptor Activity
  • SH2 Domain Binding
  • Phospholipase Binding
  • Protein Tyrosine Kinase Binding
Biological Process
  • Inflammatory Response
  • Humoral Immune Response
  • Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
  • Positive Regulation Of Gene Expression
  • B Cell Differentiation
  • Intracellular Signal Transduction
  • B Cell Receptor Signaling Pathway
Pathways
  • Regulation of signaling by CBL
  • Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
  • Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
GWAS
  • Mean spheric corpuscular volume ( 32888494)
Interacting Genes 25 interacting genes: AR BTK CBL CBLB CD72 CD79A CMTM3 CRKL EGFR ERBB2 ERBB3 GAB1 GRAP2 GRB2 ITK KIT LCP2 MAP4K1 NCK1 PLCG1 PLCG2 PTPN6 SH3KBP1 SYK VAV1
Entrez ID 29760
HPRD ID 05153
Ensembl ID ENSG00000095585
Uniprot IDs Q2MD54 Q2MD59 Q8WV28
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025