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LAMTOR2

Description late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
Image
GO Annotations Cellular Component
  • Lysosomal Membrane
  • Late Endosome
  • Plasma Membrane
  • Endosome Membrane
  • Specific Granule Membrane
  • Tertiary Granule Membrane
  • Ragulator Complex
Molecular Function
  • Guanyl-nucleotide Exchange Factor Activity
  • Protein Binding
  • Molecular Adaptor Activity
Biological Process
  • Regulation Of Cell Growth
  • Fibroblast Migration
  • Positive Regulation Of TOR Signaling
  • Cellular Protein Localization
  • Positive Regulation Of MAPK Cascade
  • Regulation Of Catalytic Activity
  • Cellular Response To Amino Acid Stimulus
  • Regulation Of Cell-substrate Junction Organization
  • Protein Localization To Cell Junction
Pathways
  • Macroautophagy
  • MTOR signalling
  • mTORC1-mediated signalling
  • Energy dependent regulation of mTOR by LKB1-AMPK
  • TP53 Regulates Metabolic Genes
  • MAP2K and MAPK activation
  • Neutrophil degranulation
  • Regulation of PTEN gene transcription
  • Amino acids regulate mTORC1
Drugs
Diseases
GWAS
Interacting Genes 3 interacting genes: BORCS6 ERBB3 LAMTOR3
Entrez ID 28956
HPRD ID 17463
Ensembl ID ENSG00000116586
Uniprot IDs Q9Y2Q5
PDB IDs 5X6U 5X6V 5Y39 5Y3A 6B9X 6EHP 6EHR 6NZD 6U62 6ULG 6WJ2 6WJ3
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025