GRIA3

Description		glutamate ionotropic receptor AMPA type subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Endocytic Vesicle Membrane AMPA Glutamate Receptor Complex Dendritic Spine Postsynaptic Membrane
	Molecular Function	Amyloid-beta Binding AMPA Glutamate Receptor Activity Ligand-gated Ion Channel Activity Signaling Receptor Activity
	Biological Process	Glutamate Receptor Signaling Pathway Ion Transmembrane Transport Ionotropic Glutamate Receptor Signaling Pathway
Pathways		Activation of AMPA receptors Trafficking of AMPA receptors Trafficking of GluR2-containing AMPA receptors Unblocking of NMDA receptors, glutamate binding and activation Unblocking of NMDA receptors, glutamate binding and activation Synaptic adhesion-like molecules
Drugs		Glutamic acid Butabarbital Ethanol Lithium cation Aniracetam Talampanel CX-717 Fluciclovine (18F) Lithium citrate Lithium succinate Lithium carbonate
Diseases
GWAS		Mortality in sepsis ( 27639821)
Interacting Genes		12 interacting genes: ADRB2 CREBBP GRIA2 GRIP1 GRIP2 GZMB LYN NSF PICK1 PPM1G SDCBP SQSTM1
Entrez ID		2892
HPRD ID		02378
Ensembl ID		ENSG00000125675
Uniprot IDs		P42263 Q17R51 Q5XKG2
PDB IDs
Enriched GO Terms of Interacting Partners?
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