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ALOX12B

Description arachidonate 12-lipoxygenase, 12R type
Image No pdb structure
GO Annotations Cellular Component
  • Cytosol
  • Perinuclear Region Of Cytoplasm
Molecular Function
  • Arachidonate 12(S)-lipoxygenase Activity
  • Iron Ion Binding
  • Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen
  • Lyase Activity
  • Isomerase Activity
  • Arachidonate 8(R)-lipoxygenase Activity
  • Arachidonate 12(R)-lipoxygenase Activity
  • Linoleate 9S-lipoxygenase Activity
Biological Process
  • Protein Lipidation
  • Sphingolipid Metabolic Process
  • Positive Regulation Of Gene Expression
  • Arachidonic Acid Metabolic Process
  • Lipoxygenase Pathway
  • Lipid Oxidation
  • Positive Regulation Of MAPK Cascade
  • Linoleic Acid Metabolic Process
  • Ceramide Biosynthetic Process
  • Hepoxilin Biosynthetic Process
  • Establishment Of Skin Barrier
  • Positive Regulation Of Mucus Secretion
Pathways
  • Synthesis of 12-eicosatetraenoic acid derivatives
Drugs
Diseases
GWAS
Interacting Genes 2 interacting genes: KRT5 LMNA
Entrez ID 242
HPRD ID 04772
Ensembl ID ENSG00000179477
Uniprot IDs O75342
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025