SPO11

Description		SPO11 initiator of meiotic double stranded breaks
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Chromosome, Telomeric Region
	Molecular Function	DNA Binding DNA Topoisomerase Type II (double Strand Cut, ATP-hydrolyzing) Activity Protein Binding ATP Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Meiotic DNA Double-strand Break Processing Ovarian Follicle Development Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Spermatid Development Female Gamete Generation Protein Localization To Chromosome Meiotic DNA Double-strand Break Formation Meiotic Telomere Clustering Oogenesis Double-strand Break Repair Involved In Meiotic Recombination
Pathways		Meiotic recombination
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494)
Interacting Genes		1 interacting genes: TCF4
Entrez ID		23626
HPRD ID		09236
Ensembl ID		ENSG00000054796
Uniprot IDs		Q9Y5K1
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?