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PRAME

Description PRAME nuclear receptor transcriptional regulator
Image No pdb structure
GO Annotations Cellular Component
  • Chromatin
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Plasma Membrane
  • Cul2-RING Ubiquitin Ligase Complex
Molecular Function
  • Protein Binding
  • Retinoic Acid Receptor Binding
  • Ubiquitin Ligase-substrate Adaptor Activity
Biological Process
  • Protein Polyubiquitination
  • Apoptotic Process
  • Positive Regulation Of Cell Population Proliferation
  • Cell Differentiation
  • Regulation Of Growth
  • Negative Regulation Of Apoptotic Process
  • Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
  • Negative Regulation Of Cell Differentiation
  • Negative Regulation Of Transcription, DNA-templated
  • Negative Regulation Of Retinoic Acid Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Interacting Genes 9 interacting genes: ELOB ELOC FBXO7 RARA RBX1 STK19 UBC XRN2 ZNF408
Entrez ID 23532
HPRD ID 05820
Ensembl ID ENSG00000185686
Uniprot IDs A0A024R1E6 B7Z7K8 B7Z986 B7ZAT0 P78395
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025