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CLCF1

Description cardiotrophin like cytokine factor 1
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Region
  • CRLF-CLCF1 Complex
  • CNTFR-CLCF1 Complex
Molecular Function
  • Signaling Receptor Binding
  • Cytokine Activity
  • Ciliary Neurotrophic Factor Receptor Binding
  • Protein Binding
  • Growth Factor Activity
Biological Process
  • Positive Regulation Of Immunoglobulin Production
  • Cell Surface Receptor Signaling Pathway
  • Receptor Signaling Pathway Via JAK-STAT
  • Positive Regulation Of Cell Population Proliferation
  • Cytokine-mediated Signaling Pathway
  • B Cell Differentiation
  • Positive Regulation Of B Cell Proliferation
  • Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
  • Negative Regulation Of Neuron Apoptotic Process
  • Positive Regulation Of Isotype Switching To IgE Isotypes
  • Positive Regulation Of Astrocyte Differentiation
Pathways
  • IL-6-type cytokine receptor ligand interactions
Drugs
Diseases
GWAS
  • Body fat distribution (arm fat ratio) ( 30664634)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Metabolite levels (lipid measures) ( 27005778)
Interacting Genes 4 interacting genes: CNTFR CRLF1 LYN SHANK2
Entrez ID 23529
HPRD ID 09643
Ensembl ID ENSG00000175505
Uniprot IDs Q9UBD9
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025