ARHGEF15

Description		Rho guanine nucleotide exchange factor 15
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Dendrite
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Stress Fiber Assembly Retina Vasculature Morphogenesis In Camera-type Eye Activation Of GTPase Activity Negative Regulation Of Synapse Maturation
Pathways		NRAGE signals death through JNK G alpha (12/13) signalling events RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Bipolar disorder ( 28115744) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Immature fraction of reticulocytes ( 32888494) LDL cholesterol ( 30275531) Platelet distribution width ( 32888494) Total cholesterol levels ( 30275531) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		14 interacting genes: C11orf49 CDC42 CEP55 DNAJC5 EPHA4 ESR1 ESRRG GORASP2 LASP1 MOB4 PIN1 PRKG1 RHOA SH3RF1
Entrez ID		22899
HPRD ID		10535
Ensembl ID		ENSG00000198844
Uniprot IDs		A0A0S2Z547 O94989
PDB IDs
Enriched GO Terms of Interacting Partners?
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