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AIF1
Description
allograft inflammatory factor 1
Image
GO Annotations
Cellular Component
Ruffle
Phagocytic Cup
Nucleus
Cytoplasm
Cytosol
Actin Filament
Lamellipodium
Ruffle Membrane
Perikaryon
Perinuclear Region Of Cytoplasm
Molecular Function
Molecular_function
Calcium Ion Binding
Protein Binding
Actin Filament Binding
Biological Process
Microglial Cell Activation
Positive Regulation Of Protein Phosphorylation
Phagocytosis, Engulfment
Inflammatory Response
Positive Regulation Of Cell Population Proliferation
Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Muscle Hyperplasia
Rac Protein Signal Transduction
Cerebellum Development
Actin Filament Polymerization
Parallel Actin Filament Bundle Assembly
Positive Regulation Of Cell Migration
Cellular Response To Extracellular Stimulus
Positive Regulation Of Chemokine Production
Positive Regulation Of Interleukin-6 Production
Cellular Response To Hormone Stimulus
Cellular Response To Oxidative Stress
Positive Regulation Of T Cell Proliferation
Negative Regulation Of Apoptotic Process
Positive Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Smooth Muscle Cell Proliferation
Negative Regulation Of Smooth Muscle Cell Proliferation
Response To Axon Injury
Positive Regulation Of Chemotaxis
Actin Filament Bundle Assembly
Response To Glucocorticoid
Response To Electrical Stimulus
Actin Crosslink Formation
Cellular Response To Morphine
Cellular Response To Interferon-gamma
Cellular Response To Hydroperoxide
Negative Regulation Of Smooth Muscle Cell Chemotaxis
Positive Regulation Of Smooth Muscle Cell Chemotaxis
Positive Regulation Of Mononuclear Cell Migration
Positive Regulation Of Monocyte Chemotaxis
Positive Regulation Of Fibroblast Growth Factor Production
Ruffle Assembly
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of T Cell Migration
Pathways
Drugs
Diseases
GWAS
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Asthma (
31619474
)
Asthma (childhood onset) (
31619474
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Blood protein levels (
29875488
)
Crohn's disease (
22936669
)
Heel bone mineral density (
30598549
)
Height (
23563607
)
Hip circumference adjusted for BMI (
34021172
)
Inflammatory bowel disease (
28067908
)
Laryngeal squamous cell carcinoma (
25194280
)
Malaria (
31844061
)
Mean platelet volume (
32888494
)
Neonatal lupus (
20662065
)
Oral cavity cancer (
27749845
)
Platelet count (
32888494
)
Rosacea symptom severity (
29771307
)
Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) (
26651848
)
Takayasu arteritis (
25604533
)
Ulcerative colitis (
28067908
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Weight (
19079260
)
Interacting Genes
2 interacting genes:
ACTA1
LCP1
Entrez ID
199
HPRD ID
03496
Ensembl ID
ENSG00000204472
Uniprot IDs
I3WTX1
P55008
Q4V347
PDB IDs
2D58
2G2B
Enriched GO Terms of Interacting Partners
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