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ABAT
Description
4-aminobutyrate aminotransferase
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Matrix
4-aminobutyrate Transaminase Complex
Neuron Projection
Molecular Function
4-aminobutyrate Transaminase Activity
Pyridoxal Phosphate Binding
Succinate-semialdehyde Dehydrogenase Binding
4-aminobutyrate:2-oxoglutarate Transaminase Activity
Identical Protein Binding
Metal Ion Binding
(S)-3-amino-2-methylpropionate Transaminase Activity
Iron-sulfur Cluster Binding
Biological Process
Response To Hypoxia
Aging
Copulation
Locomotory Behavior
Response To Xenobiotic Stimulus
Gamma-aminobutyric Acid Metabolic Process
Gamma-aminobutyric Acid Biosynthetic Process
Gamma-aminobutyric Acid Catabolic Process
Response To Iron Ion
Negative Regulation Of Gamma-aminobutyric Acid Secretion
Cerebellum Development
Positive Regulation Of Heat Generation
Positive Regulation Of Insulin Secretion
Negative Regulation Of Dopamine Secretion
Response To Nicotine
Exploration Behavior
Neurotransmitter Catabolic Process
Response To Ethanol
Negative Regulation Of Blood Pressure
Positive Regulation Of Dopamine Metabolic Process
Behavioral Response To Cocaine
Positive Regulation Of Uterine Smooth Muscle Contraction
Negative Regulation Of Platelet Aggregation
Positive Regulation Of Inhibitory Postsynaptic Potential
Positive Regulation Of Prolactin Secretion
Positive Regulation Of Aspartate Secretion
Pathways
Degradation of GABA
Drugs
Pyridoxal phosphate
Pyruvic acid
Glutamic acid
Alanine
Phenelzine
Vigabatrin
(4e)-4-Aminohex-4-Enoic Acid
4-Amino Hexanoic Acid
Diseases
GWAS
Anger (
24489884
)
Bronchopulmonary dysplasia in preterm infants (
30113228
)
Menopause (age at onset) (
26414677
)
Response to opioid analgesics in cancer (pain decrease) (
30277654
)
Interacting Genes
1 interacting genes:
ALDH5A1
Entrez ID
18
HPRD ID
00661
Ensembl ID
ENSG00000183044
Uniprot IDs
P80404
X5D8S1
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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