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SIK1
Description
salt inducible kinase 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Molecular Function
Magnesium Ion Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
CAMP Response Element Binding Protein Binding
Protein Kinase Binding
14-3-3 Protein Binding
Protein Serine Kinase Activity
Biological Process
Regulation Of Sodium Ion Transport
Protein Phosphorylation
Cell Cycle
Regulation Of Mitotic Cell Cycle
Regulation Of Myotube Differentiation
Negative Regulation Of Triglyceride Biosynthetic Process
Negative Regulation Of CREB Transcription Factor Activity
Intracellular Signal Transduction
Cellular Response To Glucose Starvation
Entrainment Of Circadian Clock By Photoperiod
Regulation Of Cell Differentiation
Negative Regulation Of Gluconeogenesis
Protein Autophosphorylation
Rhythmic Process
Cardiac Muscle Cell Differentiation
Positive Regulation Of Anoikis
Pathways
Circadian Clock
Drugs
Dabrafenib
Fostamatinib
Diseases
GWAS
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Alzheimer disease and age of onset (
26830138
)
Blond vs. brown/black hair color (
30531825
)
Diastolic blood pressure (
28135244
27841878
28739976
27618452
)
Eye color (
33692100
)
Red vs. brown/black hair color (
30531825
)
Systolic blood pressure (
27841878
28739976
27618452
)
Interacting Genes
13 interacting genes:
CRTC2
GINS4
HDAC5
MAPT
MCM2
NMNAT1
PRKACA
RNF2
RPL3
STK11
SUPT5H
VAPA
YWHAZ
Entrez ID
150094
HPRD ID
09301
Ensembl ID
ENSG00000142178
Uniprot IDs
P57059
PDB IDs
Enriched GO Terms of Interacting Partners
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