AEBP2

Description		AE binding protein 2
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GO Annotations	Cellular Component	Chromatin Nucleoplasm ESC/E(Z) Complex
	Molecular Function	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription By RNA Polymerase II
Pathways		PRC2 methylates histones and DNA PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Chronic mountain sickness ( 31417607) Diastolic blood pressure ( 30224653) Diverticular disease ( 30177863) Height ( 28552196) Lung function (FEV1/FVC) ( 30804560) Manganese levels ( 26025379) Obesity-related traits ( 23251661) Opioid use cessation ( 31936517) Pulmonary function ( 21946350) Response to fenofibrate (LDL cholesterol levels) ( 27002377) Schizophrenia, bipolar disorder or major depressive disorder ( 34099189)
Interacting Genes		18 interacting genes: APP EED H1-1 H1-2 HMBOX1 JMJD6 KRTAP10-8 LDOC1 MDFI PICK1 RALYL RBBP4 SUZ12 THAP1 TRIM55 TRIM63 TSPYL2 ZNF408
Entrez ID		121536
HPRD ID		16477
Ensembl ID		ENSG00000139154
Uniprot IDs		Q6ZN18
PDB IDs		5WAI 5Y0U 5Y1U 6C23 6C24 6WKR 7KSO
Enriched GO Terms of Interacting Partners?
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