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CEP43

Description centrosomal protein 43
Image
GO Annotations Cellular Component
  • Nucleus
  • Centrosome
  • Centriole
  • Cytosol
  • Cell Projection
  • Perinuclear Region Of Cytoplasm
Molecular Function
  • Protein Binding
  • Protein Kinase Binding
  • Protein Tyrosine Kinase Inhibitor Activity
  • Protein Homodimerization Activity
Biological Process
  • Negative Regulation Of Protein Kinase Activity
  • Positive Regulation Of Cell Population Proliferation
  • Cell Projection Organization
  • Positive Regulation Of Cell Growth
  • Positive Regulation Of Cell Migration
  • Microtubule Anchoring
  • Negative Regulation Of Protein Tyrosine Kinase Activity
Pathways
  • Signaling by cytosolic FGFR1 fusion mutants
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • Signaling by FGFR1 in disease
  • AURKA Activation by TPX2
Drugs
Diseases
GWAS
Interacting Genes 10 interacting genes: CEP19 LINC01558 NAGK OGT PPP2R1B RNASET2 S100A6 TBP TCP10L3 VASP
Entrez ID 11116
HPRD ID 10392
Ensembl ID ENSG00000213066
Uniprot IDs A0A087WV25 B4DH64 O95684
PDB IDs 2D68
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025