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SIGMAR1

Description sigma non-opioid intracellular receptor 1
Image
GO Annotations Cellular Component
  • Nuclear Envelope
  • Nuclear Inner Membrane
  • Nuclear Outer Membrane
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Lipid Droplet
  • Cytosol
  • Postsynaptic Density
  • Membrane
  • Integral Component Of Membrane
  • Growth Cone
  • Cytoplasmic Vesicle
  • Postsynaptic Density Membrane
Molecular Function
  • G Protein-coupled Opioid Receptor Activity
  • Protein Binding
Biological Process
  • Lipid Transport
  • Nervous System Development
  • Cell Death In Response To Hydrogen Peroxide
  • G Protein-coupled Opioid Receptor Signaling Pathway
  • Regulation Of Neuron Apoptotic Process
  • Protein Homotrimerization
Pathways
  • Potential therapeutics for SARS
Drugs
  • Amitriptyline
  • Remoxipride
  • Haloperidol
  • Dextromethorphan
  • Nortriptyline
  • Fenfluramine
  • Pentazocine
  • Cocaine
  • Hydrocodone
  • Sertraline
  • Dimethyltryptamine
  • Prasterone
  • Phencyclidine
  • Noscapine
  • Captodiame
  • Pentoxyverine
Diseases
GWAS
Interacting Genes 14 interacting genes: ANK2 DCAF12 DNAJB5 GHSR GNE ITPR3 NFX1 PDZD11 PHF24 RECK RUSC2 SPAG8 SPINK4 VCP
Entrez ID 10280
HPRD ID 03580
Ensembl ID ENSG00000147955
Uniprot IDs A2A3U5 B4DR71 Q99720
PDB IDs 5HK1 5HK2 6DJZ 6DK0 6DK1
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025