WNT5A - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Associated Diseases Hide
Novel	ACVR2B	activin A receptor type 2B	Signaling by NODAL Regulation of signaling by NODAL Signaling by Activin Signaling by Activin Signaling by BMP	Heterotaxy; Situs ambiguus
Novel	GPR27	G protein-coupled receptor 27	G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Novel	IMPG1	interphotoreceptor matrix proteoglycan 1
Novel	LHFPL6	LHFPL tetraspan subfamily member 6
Novel	PTPRG	protein tyrosine phosphatase receptor type G
Novel	SELENBP1	selenium binding protein 1
	FZD1	frizzled class receptor 1	TCF dependent signaling in response to WNT Class B/2 (Secretin family receptors) PCP/CE pathway PCP/CE pathway Asymmetric localization of PCP proteins Disassembly of the destruction complex and recruitment of AXIN to the membrane Disassembly of the destruction complex and recruitment of AXIN to the membrane
	FZD5	frizzled class receptor 5	Class B/2 (Secretin family receptors) Ca2+ pathway Ca2+ pathway Asymmetric localization of PCP proteins Disassembly of the destruction complex and recruitment of AXIN to the membrane Regulation of FZD by ubiquitination WNT5A-dependent internalization of FZD2, FZD5 and ROR2 Signaling by RNF43 mutants
	ROR2	receptor tyrosine kinase like orphan receptor 2	PCP/CE pathway WNT5A-dependent internalization of FZD2, FZD5 and ROR2	Brachydactyly, including: type A; type B; type D; type E Robinow syndrome

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