Search Results for: PPP1R16B

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel CDK5RAP1 CDK5 regulatory subunit associated protein 1
Novel FAM83D family with sequence similarity 83 member D
Novel MCEE methylmalonyl-CoA epimerase
  • Propionyl-CoA catabolism
  • Methylmalonic aciduria (MMA)
Novel MYL9 myosin light chain 9
  • EPHA-mediated growth cone collapse
  • Sema4D induced cell migration and growth-cone collapse
  • Smooth Muscle Contraction
  • RHO GTPases activate PKNs
  • RHO GTPases activate CIT
  • RHO GTPases Activate ROCKs
  • RHO GTPases activate PAKs
  • RHO GTPases activate PAKs
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Novel NFX1 nuclear transcription factor, X-box binding 1
Novel SSR4 signal sequence receptor subunit 4
  • SRP-dependent cotranslational protein targeting to membrane
Novel TTI1 TELO2 interacting protein 1
Novel TUFM Tu translation elongation factor, mitochondrial
  • Mitochondrial translation elongation
  • Zinc
  • Guanosine-5'-Diphosphate
  • Zinc acetate
  • Zinc chloride
  • Zinc sulfate, unspecified form
  • Combined oxidative phosphorylation deficiency (COXPD)
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
  • Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
CDCA7L cell division cycle associated 7 like
CEP55 centrosomal protein 55
CEP70 centrosomal protein 70
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • AURKA Activation by TPX2
CRX cone-rod homeobox
  • Leber congenital amaurosis (LCR)
  • Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
DVL2 dishevelled segment polarity protein 2
  • TCF dependent signaling in response to WNT
  • WNT mediated activation of DVL
  • Signaling by Hippo
  • PCP/CE pathway
  • PCP/CE pathway
  • Asymmetric localization of PCP proteins
  • Degradation of DVL
  • Disassembly of the destruction complex and recruitment of AXIN to the membrane
  • Disassembly of the destruction complex and recruitment of AXIN to the membrane
  • WNT5A-dependent internalization of FZD4
  • Negative regulation of TCF-dependent signaling by DVL-interacting proteins
  • RHO GTPases Activate Formins
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
  • WNT5:FZD7-mediated leishmania damping
  • WNT5:FZD7-mediated leishmania damping
DVL3 dishevelled segment polarity protein 3
  • TCF dependent signaling in response to WNT
  • WNT mediated activation of DVL
  • PCP/CE pathway
  • PCP/CE pathway
  • Degradation of DVL
  • Disassembly of the destruction complex and recruitment of AXIN to the membrane
  • Disassembly of the destruction complex and recruitment of AXIN to the membrane
  • Negative regulation of TCF-dependent signaling by DVL-interacting proteins
  • RHO GTPases Activate Formins
  • WNT5:FZD7-mediated leishmania damping
  • WNT5:FZD7-mediated leishmania damping
FAM83A family with sequence similarity 83 member A
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial
  • Mitochondrial tRNA aminoacylation
  • Phenylalanine
FLYWCH1 FLYWCH-type zinc finger 1
GATA1 GATA binding protein 1
  • RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • Factors involved in megakaryocyte development and platelet production
  • Thrombocytopenia (THC); Familial platelet disorder with associated myeloid malignancy (FPDMM)
  • Congenital dyserythropoietic anemias (CDAs)
GFAP glial fibrillary acidic protein
  • Nuclear signaling by ERBB4
  • Chaperone Mediated Autophagy
  • Alexander disease

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