Search Results for: DSC2

12 interactions involving DSC2 - desmocollin 2 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel CDC6 cell division cycle 6
  • Transcription of E2F targets under negative control by DREAM complex
  • Activation of ATR in response to replication stress
  • CDC6 association with the ORC:origin complex
  • CDT1 association with the CDC6:ORC:origin complex
  • Assembly of the pre-replicative complex
  • Orc1 removal from chromatin
  • Activation of the pre-replicative complex
  • CDK-mediated phosphorylation and removal of Cdc6
  • G1/S-Specific Transcription
Novel CELF4 CUGBP Elav-like family member 4
Novel DSC3 desmocollin 3
  • Keratinization
  • Formation of the cornified envelope
  • Hypotrichosis and recurrent skin vesicles
Novel FHOD3 formin homology 2 domain containing 3
Novel ITSN1 intersectin 1
  • NRAGE signals death through JNK
  • Rho GTPase cycle
  • EPHB-mediated forward signaling
  • EPHB-mediated forward signaling
  • G alpha (12/13) signalling events
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
Novel RO60 Ro60, Y RNA binding protein
CLK1 CDC like kinase 1
  • Debromohymenialdisine
  • CHGN111
  • ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate
  • Fostamatinib
DSG1 desmoglein 1
  • Apoptotic cleavage of cell adhesion proteins
  • Neutrophil degranulation
  • Keratinization
  • Formation of the cornified envelope
  • Striate palmoplantar keratoderma
DSG2 desmoglein 2
  • Apoptotic cleavage of cell adhesion proteins
  • Keratinization
  • Formation of the cornified envelope
  • Arrhythmogenic right ventricular cardiomyopathy (ARVC)
JUP junction plakoglobin
  • Adherens junctions interactions
  • VEGFR2 mediated vascular permeability
  • Neutrophil degranulation
  • Keratinization
  • Formation of the cornified envelope
  • Zinc
  • Zinc acetate
  • Arrhythmogenic right ventricular cardiomyopathy (ARVC)
  • Naxos disease and Carvajal syndrome
PKP2 plakophilin 2
  • Keratinization
  • Formation of the cornified envelope
  • Arrhythmogenic right ventricular cardiomyopathy (ARVC)
PKP3 plakophilin 3
  • Keratinization
  • Formation of the cornified envelope

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