Search Results for: NIF3L1

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
SSX2IP SSX family member 2 interacting protein
STAT3 signal transducer and activator of transcription 3
  • Interleukin-6 signaling
  • BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
  • Interleukin-7 signaling
  • Interleukin-7 signaling
  • Signaling by SCF-KIT
  • Signaling by cytosolic FGFR1 fusion mutants
  • Downstream signal transduction
  • Signalling to STAT3
  • Senescence-Associated Secretory Phenotype (SASP)
  • Signaling by Leptin
  • POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
  • Association of TriC/CCT with target proteins during biosynthesis
  • Transcriptional regulation of pluripotent stem cells
  • Interleukin-10 signaling
  • Interleukin-4 and Interleukin-13 signaling
  • PTK6 Activates STAT3
  • PTK6 Activates STAT3
  • Interleukin-20 family signaling
  • MET activates STAT3
  • MET activates STAT3
  • Interleukin-15 signaling
  • Interleukin-35 Signalling
  • Interleukin-9 signaling
  • Interleukin-37 signaling
  • Interleukin-23 signaling
  • Interleukin-23 signaling
  • Interleukin-27 signaling
  • Interleukin-21 signaling
  • Transcriptional regulation of granulopoiesis
  • Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants
  • Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants
  • Signaling by PDGFRA extracellular domain mutants
  • Growth hormone receptor signaling
  • ENMD-1198
  • Other well-defined immunodeficiency syndromes, including the following seven diseases: Wiskott-Aldrich syndrome; DiGeorge syndrome; Hyper-IgE syndrome; X-linked lymphoproliferative syndrome; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-linked Syndrome (IPEX); Cartilage-Hair Hypoplasia; Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
  • Oral cancer
STK16 serine/threonine kinase 16
  • Fostamatinib
SULT1A2 sulfotransferase family 1A member 2
  • Cytosolic sulfonation of small molecules
SULT1A3 sulfotransferase family 1A member 3
  • Cytosolic sulfonation of small molecules
  • XBP1(S) activates chaperone genes
  • Cytosolic sulfonation of small molecules
SULT2A1 sulfotransferase family 2A member 1
  • Cytosolic sulfonation of small molecules
  • PPARA activates gene expression
  • Adenosine 3',5'-diphosphate
  • Aetiocholanolone
  • Mercuric iodide
SYT17 synaptotagmin 17
TCL1A TCL1 family AKT coactivator A
THOC7 THO complex 7
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
  • mRNA 3'-end processing
  • RNA Polymerase II Transcription Termination
TIFA TRAF interacting protein with forkhead associated domain
  • Alpha-protein kinase 1 signaling pathway
TRAF2 TNF receptor associated factor 2
  • Caspase activation via Death Receptors in the presence of ligand
  • Regulation by c-FLIP
  • RIPK1-mediated regulated necrosis
  • CASP8 activity is inhibited
  • TNFR1-induced proapoptotic signaling
  • Regulation of TNFR1 signaling
  • TNFR1-induced NFkappaB signaling pathway
  • TNFR2 non-canonical NF-kB pathway
  • Regulation of necroptotic cell death
  • TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
  • Ub-specific processing proteases
  • Dimerization of procaspase-8
  • TNF signaling
  • TRAF6 mediated IRF7 activation
  • TRAF6 mediated NF-kB activation
  • TRAF6 mediated NF-kB activation
  • Defective RIPK1-mediated regulated necrosis
TRIM21 tripartite motif containing 21
  • STING mediated induction of host immune responses
  • Regulation of innate immune responses to cytosolic DNA
  • Interferon gamma signaling
  • Antigen processing: Ubiquitination & Proteasome degradation
TRIM27 tripartite motif containing 27
  • SUMOylation of ubiquitinylation proteins
  • Regulation of PTEN stability and activity
  • Suppression of apoptosis
TRIP13 thyroid hormone receptor interactor 13
TSC22D4 TSC22 domain family member 4
TXN thioredoxin
  • Oxidative Stress Induced Senescence
  • Detoxification of Reactive Oxygen Species
  • Interconversion of nucleotide di- and triphosphates
  • TP53 Regulates Metabolic Genes
  • Protein repair
  • The NLRP3 inflammasome
  • The NLRP3 inflammasome
  • Regulation of FOXO transcriptional activity by acetylation
  • Purinergic signaling in leishmaniasis infection
  • Purinergic signaling in leishmaniasis infection
  • Phenethyl Isothiocyanate
VIM vimentin
  • Caspase-mediated cleavage of cytoskeletal proteins
  • Striated Muscle Contraction
  • Interleukin-4 and Interleukin-13 signaling
  • Chaperone Mediated Autophagy
  • Late endosomal microautophagy
  • Aggrephagy
  • Artenimol
  • Phenethyl Isothiocyanate
YES1 YES proto-oncogene 1, Src family tyrosine kinase
  • Signaling by ERBB2
  • Signaling by SCF-KIT
  • Signaling by SCF-KIT
  • Regulation of KIT signaling
  • FCGR activation
  • PECAM1 interactions
  • EPH-Ephrin signaling
  • CD28 co-stimulation
  • CTLA4 inhibitory signaling
  • EPHB-mediated forward signaling
  • EPHB-mediated forward signaling
  • EPHA-mediated growth cone collapse
  • EPHA-mediated growth cone collapse
  • EPH-ephrin mediated repulsion of cells
  • RUNX2 regulates osteoblast differentiation
  • Regulation of signaling by CBL
  • Regulation of signaling by CBL
  • FCGR3A-mediated IL10 synthesis
  • FCGR3A-mediated phagocytosis
  • Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants
  • Dasatinib
  • Fostamatinib
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  • Activation of BAD and translocation to mitochondria
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • RHO GTPases activate PKNs
  • TP53 Regulates Metabolic Genes
  • Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
  • Regulation of localization of FOXO transcription factors
  • Phenethyl Isothiocyanate
ZBED1 zinc finger BED-type containing 1
  • SUMOylation of chromatin organization proteins

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