Search Results for: PCM1

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
RBM5 RNA binding motif protein 5
  • mRNA Splicing - Major Pathway
RINT1 RAD50 interactor 1
  • COPI-dependent Golgi-to-ER retrograde traffic
RPA2 replication protein A2
  • Translesion synthesis by REV1
  • Recognition of DNA damage by PCNA-containing replication complex
  • Translesion Synthesis by POLH
  • Removal of the Flap Intermediate from the C-strand
  • Activation of ATR in response to replication stress
  • Regulation of HSF1-mediated heat shock response
  • HSF1 activation
  • Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
  • Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
  • Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
  • PCNA-Dependent Long Patch Base Excision Repair
  • Translesion synthesis by POLK
  • Translesion synthesis by POLI
  • Termination of translesion DNA synthesis
  • HDR through Single Strand Annealing (SSA)
  • HDR through Homologous Recombination (HRR)
  • Processing of DNA double-strand break ends
  • Presynaptic phase of homologous DNA pairing and strand exchange
  • Formation of Incision Complex in GG-NER
  • Gap-filling DNA repair synthesis and ligation in GG-NER
  • Dual Incision in GG-NER
  • Dual incision in TC-NER
  • Gap-filling DNA repair synthesis and ligation in TC-NER
  • Fanconi Anemia Pathway
  • Regulation of TP53 Activity through Phosphorylation
  • Activation of the pre-replicative complex
  • Removal of the Flap Intermediate
  • G2/M DNA damage checkpoint
  • Meiotic recombination
TFIP11 tuftelin interacting protein 11
  • mRNA Splicing - Major Pathway
TTC8 tetratricopeptide repeat domain 8
  • BBSome-mediated cargo-targeting to cilium
  • Bardet-Biedl syndrome (BBS)
WASHC3 WASH complex subunit 3
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  • Activation of BAD and translocation to mitochondria
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • Signaling by Hippo
  • NADE modulates death signalling
  • Regulation of PLK1 Activity at G2/M Transition
  • Regulation of HSF1-mediated heat shock response
  • HSF1 activation
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • RHO GTPases activate PKNs
  • TP53 Regulates Metabolic Genes
  • Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
  • AURKA Activation by TPX2
  • Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
  • RAB GEFs exchange GTP for GDP on RABs
  • Fusicoccin
  • Phenethyl Isothiocyanate
  • Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  • Activation of BAD and translocation to mitochondria
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • RHO GTPases activate PKNs
  • TP53 Regulates Metabolic Genes
  • Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
  • Regulation of localization of FOXO transcription factors
  • Phenethyl Isothiocyanate

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