|
RBM5 |
RNA binding motif protein 5 |
- mRNA Splicing - Major Pathway
|
|
|
|
RINT1 |
RAD50 interactor 1 |
- COPI-dependent Golgi-to-ER retrograde traffic
|
|
|
|
RPA2 |
replication protein A2 |
- Translesion synthesis by REV1
- Recognition of DNA damage by PCNA-containing replication complex
- Translesion Synthesis by POLH
- Removal of the Flap Intermediate from the C-strand
- Activation of ATR in response to replication stress
- Regulation of HSF1-mediated heat shock response
- HSF1 activation
- Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
- Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
- Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
- PCNA-Dependent Long Patch Base Excision Repair
- Translesion synthesis by POLK
- Translesion synthesis by POLI
- Termination of translesion DNA synthesis
- HDR through Single Strand Annealing (SSA)
- HDR through Homologous Recombination (HRR)
- Processing of DNA double-strand break ends
- Presynaptic phase of homologous DNA pairing and strand exchange
- Formation of Incision Complex in GG-NER
- Gap-filling DNA repair synthesis and ligation in GG-NER
- Dual Incision in GG-NER
- Dual incision in TC-NER
- Gap-filling DNA repair synthesis and ligation in TC-NER
- Fanconi Anemia Pathway
- Regulation of TP53 Activity through Phosphorylation
- Activation of the pre-replicative complex
- Removal of the Flap Intermediate
- G2/M DNA damage checkpoint
- Meiotic recombination
|
|
|
|
TFIP11 |
tuftelin interacting protein 11 |
- mRNA Splicing - Major Pathway
|
|
|
|
TTC8 |
tetratricopeptide repeat domain 8 |
- BBSome-mediated cargo-targeting to cilium
|
|
- Bardet-Biedl syndrome (BBS)
|
|
WASHC3 |
WASH complex subunit 3 |
|
|
|
|
YWHAE |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon |
- Activation of BAD and translocation to mitochondria
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- Signaling by Hippo
- NADE modulates death signalling
- Regulation of PLK1 Activity at G2/M Transition
- Regulation of HSF1-mediated heat shock response
- HSF1 activation
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Anchoring of the basal body to the plasma membrane
- RHO GTPases activate PKNs
- TP53 Regulates Metabolic Genes
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
- AURKA Activation by TPX2
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
- RAB GEFs exchange GTP for GDP on RABs
|
- Fusicoccin
- Phenethyl Isothiocyanate
|
- Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
|
|
YWHAQ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta |
- Activation of BAD and translocation to mitochondria
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- RHO GTPases activate PKNs
- TP53 Regulates Metabolic Genes
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
- Regulation of localization of FOXO transcription factors
|
|
|