NIF3L1 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
GNMT	glycine N-methyltransferase	Metabolism of ingested SeMet, Sec, MeSec into H2Se Glyoxylate metabolism and glycine degradation	Ademetionine Glycine S-adenosyl-L-homocysteine	Hypermethioninemia; Methionine adenosyltransferase deficiency; S-adenosylhomocysteine hydrolase deficiency
GRB2	growth factor receptor bound protein 2	Interleukin-15 signaling Interleukin-15 signaling STAT5 activation downstream of FLT3 ITD mutants Signaling by FLT3 ITD and TKD mutants Signaling by FLT3 ITD and TKD mutants	Pegademase 4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid
IP6K3	inositol hexakisphosphate kinase 3	Synthesis of pyrophosphates in the cytosol
KCNIP1	potassium voltage-gated channel interacting protein 1	Phase 1 - inactivation of fast Na+ channels
KCTD17	potassium channel tetramerization domain containing 17
KCTD7	potassium channel tetramerization domain containing 7	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
KCTD9	potassium channel tetramerization domain containing 9
KRT15	keratin 15	Keratinization Formation of the cornified envelope
KXD1	KxDL motif containing 1
LAMTOR3	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3	Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes MAP2K and MAPK activation Neutrophil degranulation Regulation of PTEN gene transcription Amino acids regulate mTORC1
LMO2	LIM domain only 2	RUNX1 regulates transcription of genes involved in differentiation of HSCs		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
LMO3	LIM domain only 3
MAGEA11	MAGE family member A11
MAPRE2	microtubule associated protein RP/EB family member 2
MLXIPL	MLX interacting protein like	PKA-mediated phosphorylation of key metabolic factors PKA-mediated phosphorylation of key metabolic factors AMPK inhibits chREBP transcriptional activation activity ChREBP activates metabolic gene expression ChREBP activates metabolic gene expression PP2A-mediated dephosphorylation of key metabolic factors
NATD1	N-acetyltransferase domain containing 1
NEK6	NIMA related kinase 6	Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation
NGB	neuroglobin	Intracellular oxygen transport
NME1	NME/NM23 nucleoside diphosphate kinase 1	Interconversion of nucleotide di- and triphosphates	Zinc 2'-Deoxyguanosine-5'-Triphosphate Selenocysteine 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate Adenosine Phosphonoacetic Acid Stavudine triphosphate Thymidine-5'- Diphosphate 2'-Deoxyguanosine-5'-Diphosphate 2',3'-dideoxy-3'-fluoro-urididine-5'-diphosphate Guanosine-5'-Diphosphate 3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate Zidovudine diphosphate Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
NME7	NME/NM23 family member 7	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes

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