Search Results for: FES

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
PPID peptidylprolyl isomerase D
  • ESR-mediated signaling
PTGES3 prostaglandin E synthase 3
  • Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
  • HSP90 chaperone cycle for steroid hormone receptors (SHR)
  • HSF1 activation
  • Attenuation phase
  • Aryl hydrocarbon receptor signalling
  • ESR-mediated signaling
  • Estrogen-dependent gene expression
  • Potential therapeutics for SARS
  • Acetaminophen
  • Grn163l
  • Copper
RASA1 RAS p21 protein activator 1
  • Downstream signal transduction
  • EPHB-mediated forward signaling
  • EPHB-mediated forward signaling
  • VEGFR2 mediated cell proliferation
  • Regulation of RAS by GAPs
  • PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
  • RASA1-related disorders, including: Parkes-Weber slndrome; Capillary malformation-arteriovenous malformation (CM-AVM); Arteriovenous fistula (AVF)
RASA3 RAS p21 protein activator 3
  • Regulation of RAS by GAPs
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
  • Signaling by BMP
  • Downregulation of TGF-beta receptor signaling
  • TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
  • Asymmetric localization of PCP proteins
  • Hedgehog 'on' state
  • Hedgehog 'on' state
  • Regulation of RUNX2 expression and activity
  • Regulation of RUNX2 expression and activity
  • Regulation of RUNX3 expression and activity
  • Antigen processing: Ubiquitination & Proteasome degradation
STAT3 signal transducer and activator of transcription 3
  • Interleukin-6 signaling
  • BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
  • Interleukin-7 signaling
  • Interleukin-7 signaling
  • Signaling by SCF-KIT
  • Signaling by cytosolic FGFR1 fusion mutants
  • Downstream signal transduction
  • Signalling to STAT3
  • Senescence-Associated Secretory Phenotype (SASP)
  • Signaling by Leptin
  • POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
  • Association of TriC/CCT with target proteins during biosynthesis
  • Transcriptional regulation of pluripotent stem cells
  • Interleukin-10 signaling
  • Interleukin-4 and Interleukin-13 signaling
  • PTK6 Activates STAT3
  • PTK6 Activates STAT3
  • Interleukin-20 family signaling
  • MET activates STAT3
  • MET activates STAT3
  • Interleukin-15 signaling
  • Interleukin-35 Signalling
  • Interleukin-9 signaling
  • Interleukin-37 signaling
  • Interleukin-23 signaling
  • Interleukin-23 signaling
  • Interleukin-27 signaling
  • Interleukin-21 signaling
  • Transcriptional regulation of granulopoiesis
  • Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants
  • Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants
  • Signaling by PDGFRA extracellular domain mutants
  • Growth hormone receptor signaling
  • ENMD-1198
  • Other well-defined immunodeficiency syndromes, including the following seven diseases: Wiskott-Aldrich syndrome; DiGeorge syndrome; Hyper-IgE syndrome; X-linked lymphoproliferative syndrome; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-linked Syndrome (IPEX); Cartilage-Hair Hypoplasia; Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
  • Oral cancer
TERF1 telomeric repeat binding factor 1
  • Recognition and association of DNA glycosylase with site containing an affected pyrimidine
  • Cleavage of the damaged pyrimidine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Recognition and association of DNA glycosylase with site containing an affected purine
  • Cleavage of the damaged purine
  • Cleavage of the damaged purine
  • Meiotic synapsis
  • Packaging Of Telomere Ends
  • Telomere Extension By Telomerase
  • Polymerase switching on the C-strand of the telomere
  • Processive synthesis on the C-strand of the telomere
  • Telomere C-strand (Lagging Strand) Synthesis
  • Telomere C-strand synthesis initiation
  • Removal of the Flap Intermediate from the C-strand
  • DNA Damage/Telomere Stress Induced Senescence
  • Inhibition of DNA recombination at telomere
TRIM28 tripartite motif containing 28
  • Generic Transcription Pathway
  • SUMOylation of transcription cofactors
  • HCMV Early Events
ZNF746 zinc finger protein 746
  • Generic Transcription Pathway
ZNF775 zinc finger protein 775
  • Generic Transcription Pathway

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