ARL13B - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
FAXDC2	fatty acid hydroxylase domain containing 2
FDFT1	farnesyl-diphosphate farnesyltransferase 1	Cholesterol biosynthesis PPARA activates gene expression Activation of gene expression by SREBF (SREBP)	TAK-475
FKBP8	FKBP prolyl isomerase 8	Ub-specific processing proteases
FUNDC2	FUN14 domain containing 2
FXYD6	FXYD domain containing ion transport regulator 6	Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
GAD2	glutamate decarboxylase 2	GABA synthesis GABA synthesis, release, reuptake and degradation MECP2 regulates transcription of genes involved in GABA signaling	Pyridoxal phosphate Glutamic acid
GIMAP1	GTPase, IMAP family member 1
GIMAP5	GTPase, IMAP family member 5
GJB2	gap junction protein beta 2	Oligomerization of connexins into connexons Transport of connexins along the secretory pathway Gap junction assembly Transport of connexons to the plasma membrane		Keratitis-ichthyosis-deafness syndrome Palmoplantar keratoderma with deafness Deafness, autosomal dominant Deafness, autosomal recessive Vohwinkel syndrome, including: Vohwinkel syndrome (VS); Vohwinkel syndrome with ichthyosis
GOSR2	golgi SNAP receptor complex member 2	COPII-mediated vesicle transport XBP1(S) activates chaperone genes Cargo concentration in the ER COPI-mediated anterograde transport Intra-Golgi traffic
GPR37L1	G protein-coupled receptor 37 like 1	Peptide ligand-binding receptors G alpha (i) signalling events
HMOX1	heme oxygenase 1	Heme degradation Interleukin-4 and Interleukin-13 signaling Iron uptake and transport Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	NADH Formic acid Biliverdine IX Alpha 12-Phenylheme 2-Phenylheme Verdoheme Stannsoporfin 1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE 1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone
HMOX2	heme oxygenase 2	Heme degradation Neutrophil degranulation Iron uptake and transport	NADH Stannsoporfin
HOMER3	homer scaffold protein 3	Neurexins and neuroligins Neurexins and neuroligins
ICMT	isoprenylcysteine carboxyl methyltransferase	Gamma carboxylation, hypusine formation and arylsulfatase activation RAS processing
ITGAM	integrin subunit alpha M	Toll Like Receptor 4 (TLR4) Cascade Cell surface interactions at the vascular wall Integrin cell surface interactions Interleukin-4 and Interleukin-13 signaling Neutrophil degranulation
JAGN1	jagunal homolog 1
KCNJ2	potassium inwardly rectifying channel subfamily J member 2	Activation of G protein gated Potassium channels Classical Kir channels Phase 4 - resting membrane potential Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	Ranolazine Miconazole Carvedilol Dronedarone	Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS) Atrial fibrillation Short QT syndrome Andersen-Tawil syndrome (ATS)
KLRG1	killer cell lectin like receptor G1	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
LEPROTL1	leptin receptor overlapping transcript like 1

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