PCM1 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
EPS8	epidermal growth factor receptor pathway substrate 8
EXOC8	exocyst complex component 8	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
FAM81A	family with sequence similarity 81 member A
FXR2	FMR1 autosomal homolog 2
GABARAP	GABA type A receptor-associated protein	Macroautophagy TBC/RABGAPs
GOLGA2	golgin A2	Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
HAP1	huntingtin associated protein 1
ING5	inhibitor of growth family member 5	HATs acetylate histones Regulation of TP53 Activity through Acetylation
KLC1	kinesin light chain 1	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
KLC4	kinesin light chain 4	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
KRT15	keratin 15	Keratinization Formation of the cornified envelope
KRT19	keratin 19	Keratinization Formation of the cornified envelope
KRT24	keratin 24	Keratinization Formation of the cornified envelope
MCRS1	microspherule protein 1	HATs acetylate histones UCH proteinases DNA Damage Recognition in GG-NER
NDC80	NDC80 kinetochore complex component	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
NECAB2	N-terminal EF-hand calcium binding protein 2
PCNT	pericentrin	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2 Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy		Microcephalic osteodysplastic primordial dwarfism, type II (MOPD II) Seckel syndrome
PRC1	protein regulator of cytokinesis 1	RHO GTPases activate CIT
PRKCI	protein kinase C iota	Pre-NOTCH Transcription and Translation p75NTR recruits signalling complexes Tight junction interactions	Tamoxifen Bisindolylmaleimide I Fostamatinib
RALBP1	ralA binding protein 1	Rho GTPase cycle

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