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EXOSC9 |
exosome component 9 |
- ATF4 activates genes in response to endoplasmic reticulum stress
- mRNA decay by 3' to 5' exoribonuclease
- Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
- Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
- KSRP (KHSRP) binds and destabilizes mRNA
- Major pathway of rRNA processing in the nucleolus and cytosol
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FTL |
ferritin light chain |
- Scavenging by Class A Receptors
- Golgi Associated Vesicle Biogenesis
- Neutrophil degranulation
- Iron uptake and transport
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- Iron Dextran
- Protoporphyrin
- Ferric pyrophosphate
- Sodium ferric gluconate complex
- Ferric pyrophosphate citrate
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- Neurodegeneration with brain iron accumulation (NBIA); Hallervorden-Spatz syndrome; Neuroferritinopathy; Aceruloplasminemia
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KHDRBS1 |
KH RNA binding domain containing, signal transduction associated 1 |
- PTK6 Regulates Proteins Involved in RNA Processing
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KNSTRN |
kinetochore localized astrin (SPAG5) binding protein |
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LIN7A |
lin-7 homolog A, crumbs cell polarity complex component |
- Dopamine Neurotransmitter Release Cycle
- Neurexins and neuroligins
- Assembly and cell surface presentation of NMDA receptors
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LIN7B |
lin-7 homolog B, crumbs cell polarity complex component |
- Dopamine Neurotransmitter Release Cycle
- RHO GTPases Activate Rhotekin and Rhophilins
- Neurexins and neuroligins
- Assembly and cell surface presentation of NMDA receptors
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LIN7C |
lin-7 homolog C, crumbs cell polarity complex component |
- Dopamine Neurotransmitter Release Cycle
- Neurexins and neuroligins
- Assembly and cell surface presentation of NMDA receptors
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MT2P1 |
metallothionein 2 pseudogene 1 |
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MTREX |
Mtr4 exosome RNA helicase |
- Major pathway of rRNA processing in the nucleolus and cytosol
- mRNA Splicing - Major Pathway
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NDN |
necdin, MAGE family member |
- Interleukin-4 and Interleukin-13 signaling
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- Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
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NFKB1 |
nuclear factor kappa B subunit 1 |
- Activation of NF-kappaB in B cells
- RIP-mediated NFkB activation via ZBP1
- Regulated proteolysis of p75NTR
- Downstream TCR signaling
- NF-kB is activated and signals survival
- Senescence-Associated Secretory Phenotype (SASP)
- FCERI mediated NF-kB activation
- DEx/H-box helicases activate type I IFN and inflammatory cytokines production
- PKMTs methylate histone lysines
- Transcriptional regulation of white adipocyte differentiation
- TAK1 activates NFkB by phosphorylation and activation of IKKs complex
- Interleukin-1 processing
- IkBA variant leads to EDA-ID
- CLEC7A (Dectin-1) signaling
- CD209 (DC-SIGN) signaling
- CLEC7A/inflammasome pathway
- MAP3K8 (TPL2)-dependent MAPK1/3 activation
- Neutrophil degranulation
- The NLRP3 inflammasome
- Transcriptional Regulation by VENTX
- Interleukin-1 signaling
- TRAF6 mediated NF-kB activation
- HCMV Early Events
- Purinergic signaling in leishmaniasis infection
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- Donepezil
- Pseudoephedrine
- Thalidomide
- Pranlukast
- HE3286
- P54
- NOX-700
- SGN-30
- Custirsen
- NF-kappaB Decoy
- Andrographolide
- Triflusal
- Glycyrrhizic acid
- Fish oil
- SC-236
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PARN |
poly(A)-specific ribonuclease |
- ATF4 activates genes in response to endoplasmic reticulum stress
- Deadenylation of mRNA
- KSRP (KHSRP) binds and destabilizes mRNA
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RPS20 |
ribosomal protein S20 |
- L13a-mediated translational silencing of Ceruloplasmin expression
- Peptide chain elongation
- SRP-dependent cotranslational protein targeting to membrane
- SRP-dependent cotranslational protein targeting to membrane
- Viral mRNA Translation
- Selenocysteine synthesis
- Major pathway of rRNA processing in the nucleolus and cytosol
- Translation initiation complex formation
- Formation of a pool of free 40S subunits
- Formation of the ternary complex, and subsequently, the 43S complex
- Ribosomal scanning and start codon recognition
- GTP hydrolysis and joining of the 60S ribosomal subunit
- Eukaryotic Translation Termination
- Regulation of expression of SLITs and ROBOs
- Response of EIF2AK4 (GCN2) to amino acid deficiency
- Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
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SMARCA4 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
- Interleukin-7 signaling
- Formation of the beta-catenin:TCF transactivating complex
- RMTs methylate histone arginines
- Chromatin modifying enzymes
- RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
- EGR2 and SOX10-mediated initiation of Schwann cell myelination
- EGR2 and SOX10-mediated initiation of Schwann cell myelination
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SNX9 |
sorting nexin 9 |
- Golgi Associated Vesicle Biogenesis
- Clathrin-mediated endocytosis
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THOP1 |
thimet oligopeptidase 1 |
- Antigen processing: Ubiquitination & Proteasome degradation
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