Search Results for: RHOA

136 interactions involving RHOA - ras homolog family member A found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
Novel ACKR2 atypical chemokine receptor 2
  • Chemokine receptors bind chemokines
Novel AMT aminomethyltransferase
  • Glycine degradation
  • Tetrahydrofolic acid
  • NADH
  • 5-methyltetrahydrofolic acid
  • Nonketotic hyperglycinemia; Glycine encephalopathy (GCE)
Novel ARF4 ADP ribosylation factor 4
  • VxPx cargo-targeting to cilium
  • VxPx cargo-targeting to cilium
  • COPI-mediated anterograde transport
  • COPI-dependent Golgi-to-ER retrograde traffic
  • Guanosine-5'-Diphosphate
Novel ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
  • Antigen processing: Ubiquitination & Proteasome degradation
Novel C1QA complement C1q A chain
  • Initial triggering of complement
  • Classical antibody-mediated complement activation
  • Regulation of Complement cascade
  • Cetuximab
  • Etanercept
  • Palivizumab
  • Daclizumab
  • Bevacizumab
  • Classic complement pathway component defects, including the following eight diseases: C1q alpha-chain deficiency; C1q beta-chain deficiency; C1q gamma-chain deficiency; C1r deficiency; C1s deficiency; C2 deficiency; C3 deficiency; C4 deficiency
Novel CAMP cathelicidin antimicrobial peptide
  • Neutrophil degranulation
  • Antimicrobial peptides
  • Selenocysteine
Novel ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
  • Phosphate bond hydrolysis by NTPDase proteins
Novel GPX1 glutathione peroxidase 1
  • Synthesis of 5-eicosatetraenoic acids
  • Synthesis of 12-eicosatetraenoic acid derivatives
  • Synthesis of 15-eicosatetraenoic acid derivatives
  • Detoxification of Reactive Oxygen Species
  • Purine catabolism
  • Glutathione
  • Glutathione
  • Glutathione disulfide
  • Cannabidiol
  • Medical Cannabis
  • Nabiximols
  • Anemia due to disorders of glutathione metabolism, including: Glucose-6-phosphate dehydrogenase (G6PD) deficiency; Glutathione peroxidase (GPX) deficiency; Gamma-glutamylcysteine synthetase (GCLC) deficiency; Glutathione synthetase (GSS) deficiency
Novel ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
  • Platelet degranulation
  • Zinc
  • Zinc acetate
  • Zinc chloride
  • Zinc sulfate, unspecified form
Novel KLRG1 killer cell lectin like receptor G1
  • Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Novel PDCD10 programmed cell death 10
  • Cerebral cavernous malformation
Novel SUB1 SUB1 regulator of transcription
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
  • Netrin-1 signaling
AKAP13 A-kinase anchoring protein 13
  • NRAGE signals death through JNK
  • Rho GTPase cycle
  • G alpha (12/13) signalling events
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
  • Rho GTPase cycle
ARHGAP1 Rho GTPase activating protein 1
  • Rho GTPase cycle
ARHGAP10 Rho GTPase activating protein 10
  • Rho GTPase cycle
  • Regulation of PAK-2p34 activity by PS-GAP/RHG10
ARHGAP11A Rho GTPase activating protein 11A
  • Rho GTPase cycle

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