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Novel |
ADK |
adenosine kinase |
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- Adenosine phosphate
- 7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE
- 5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE
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Novel |
BET1 |
Bet1 golgi vesicular membrane trafficking protein |
- COPII-mediated vesicle transport
- COPI-mediated anterograde transport
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Novel |
H2AJ |
H2A.J histone |
- Recognition and association of DNA glycosylase with site containing an affected pyrimidine
- Cleavage of the damaged pyrimidine
- Recognition and association of DNA glycosylase with site containing an affected purine
- Recognition and association of DNA glycosylase with site containing an affected purine
- Cleavage of the damaged purine
- Cleavage of the damaged purine
- Meiotic synapsis
- Packaging Of Telomere Ends
- Pre-NOTCH Transcription and Translation
- Formation of the beta-catenin:TCF transactivating complex
- Formation of the beta-catenin:TCF transactivating complex
- PRC2 methylates histones and DNA
- Condensation of Prophase Chromosomes
- Oxidative Stress Induced Senescence
- Senescence-Associated Secretory Phenotype (SASP)
- DNA Damage/Telomere Stress Induced Senescence
- RMTs methylate histone arginines
- SIRT1 negatively regulates rRNA expression
- ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
- NoRC negatively regulates rRNA expression
- NoRC negatively regulates rRNA expression
- B-WICH complex positively regulates rRNA expression
- DNA methylation
- Transcriptional regulation by small RNAs
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- Deposition of new CENPA-containing nucleosomes at the centromere
- RNA Polymerase I Promoter Opening
- RNA Polymerase I Promoter Escape
- RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- Estrogen-dependent gene expression
- Meiotic recombination
- Transcriptional regulation of granulopoiesis
- Inhibition of DNA recombination at telomere
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Novel |
RECQL |
RecQ like helicase |
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Novel |
SPIRE1 |
spire type actin nucleation factor 1 |
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ARHGEF9 |
Cdc42 guanine nucleotide exchange factor 9 |
- NRAGE signals death through JNK
- Rho GTPase cycle
- G alpha (12/13) signalling events
- GABA receptor activation
- GABA receptor activation
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- Hyperekplexia
- Early infantile epileptic encephalopathy; Ohtahara syndrome
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BLOC1S6 |
biogenesis of lysosomal organelles complex 1 subunit 6 |
- Golgi Associated Vesicle Biogenesis
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CCDC186 |
coiled-coil domain containing 186 |
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CCDC88B |
coiled-coil domain containing 88B |
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CCDC92 |
coiled-coil domain containing 92 |
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CEP250 |
centrosomal protein 250 |
- Regulation of PLK1 Activity at G2/M Transition
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- Anchoring of the basal body to the plasma membrane
- AURKA Activation by TPX2
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CEP350 |
centrosomal protein 350 |
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DES |
desmin |
- Striated Muscle Contraction
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- Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
- Myofibrillar myopathies (MFM), including: Desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Myotilinopathy (MFM3); Zaspopathy (MFM4); Filaminopathy (MFM5); Bag3opathy
- Scapuloperoneal myopathy (SPM)
- Dilated cardiomyopathy (DCM)
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EVPL |
envoplakin |
- Formation of the cornified envelope
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EXTL3 |
exostosin like glycosyltransferase 3 |
- XBP1(S) activates chaperone genes
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KANSL1 |
KAT8 regulatory NSL complex subunit 1 |
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KIF3A |
kinesin family member 3A |
- Translocation of SLC2A4 (GLUT4) to the plasma membrane
- MHC class II antigen presentation
- Hedgehog 'off' state
- Intraflagellar transport
- Activation of SMO
- Activation of SMO
- COPI-dependent Golgi-to-ER retrograde traffic
- Kinesins
- Kinesins
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KRT19 |
keratin 19 |
- Keratinization
- Formation of the cornified envelope
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KRT20 |
keratin 20 |
- Keratinization
- Formation of the cornified envelope
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KTN1 |
kinectin 1 |
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- RHO GTPases activate KTN1
- Post-translational protein phosphorylation
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