NUP58 and USP12

Data Source:
BioGRID (proximity labelling technology)

		NUP58	USP12
Description		nucleoporin 58	ubiquitin specific peptidase 12
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GO Annotations	Cellular Component	Nuclear Envelope Nuclear Pore Nuclear Membrane Host Cell	Cellular_component Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Protein-containing Complex Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Glycolytic Process MRNA Export From Nucleus TRNA Export From Nucleus Viral Process Protein Sumoylation Viral Transcription Regulation Of Protein Import Into Nucleus Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat	Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination Protein Phosphopantetheinylation
Pathways			Ub-specific processing proteases
Drugs
Diseases
GWAS			Alcohol dependence ( 21314694) Anti-saccade response ( 29064472) Mortality in sepsis ( 27639821) Nose morphology ( 29921221) Ulcerative colitis ( 19915573)
Interacting Genes		19 interacting genes: ABI3 AGR2 APC COG3 COG6 HTT KRT27 KRT28 KRT33B MAPK3 MEIS2 MIS18A NUP62 PKNOX1 PKNOX2 TRAF1 TRIM54 UBQLN1 UBQLN2	6 interacting genes: APP H2AC20 H2BC21 NOTCH1 UBC WDR20
Entrez ID		9818	219333
HPRD ID		06355	15631
Ensembl ID		ENSG00000139496	ENSG00000152484
Uniprot IDs		Q9BVL2	O75317
PDB IDs		4JO7 4JO9 4JQ5 5IJN 5IJO	5K16 5K1A 5K1B 5K1C 5L8W
Enriched GO Terms of Interacting Partners?
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