CENPF and SLC30A1

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)

		CENPF	SLC30A1
Description		centromere protein F	solute carrier family 30 member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Chromatin Spindle Pole Condensed Chromosome Outer Kinetochore Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Centrosome Spindle Cytosol Axoneme Nuclear Matrix Midbody Ciliary Basal Body Pronucleus Perinuclear Region Of Cytoplasm Ciliary Transition Fiber	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Membrane T-tubule Nuclear Membrane Schaffer Collateral - CA1 Synapse Integral Component Of Postsynaptic Density Membrane
	Molecular Function	Chromatin Binding Protein Binding Microtubule Binding Protein C-terminus Binding Transcription Factor Binding Protein Homodimerization Activity Dynein Complex Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding Calcium Channel Inhibitor Activity
	Biological Process	Mitotic Cell Cycle Kidney Development Chromosome Segregation Mitotic Spindle Assembly Checkpoint Muscle Organ Development Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Regulation Of Striated Muscle Tissue Development Ventricular System Development Cell Differentiation Response To Drug Negative Regulation Of Transcription, DNA-templated Cell Division Metaphase Plate Congression Kinetochore Assembly Regulation Of Cell Cycle DNA Biosynthetic Process	In Utero Embryonic Development Zinc Ion Transport Cellular Calcium Ion Homeostasis Cellular Zinc Ion Homeostasis Detoxification Of Zinc Ion Negative Regulation Of Neurotransmitter Secretion Calcium Ion Import Cadmium Ion Transmembrane Transport Zinc Ion Transmembrane Transport Negative Regulation Of Zinc Ion Transmembrane Import Detoxification Of Cadmium Ion Negative Regulation Of Calcium Ion Import
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Polo-like kinase mediated events Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Zinc efflux and compartmentalization by the SLC30 family
Drugs
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Lung function (FVC) ( 30061609) Response to antineoplastic agents ( 21659360) Serum immune biomarker levels ( 32066700)	Hypertension ( 21347282)
Interacting Genes		10 interacting genes: BRAP CENPE CHMP2B FNTA FNTB NDEL1 NUP133 SNAP25 SVIL TOP3B	2 interacting genes: MTNR1A MTNR1B
Entrez ID		1063	7779
HPRD ID		02582	15366
Ensembl ID		ENSG00000117724	ENSG00000170385
Uniprot IDs		P49454	Q9Y6M5
PDB IDs
Enriched GO Terms of Interacting Partners?
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