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PTGES

Description prostaglandin E synthase
Image
GO Annotations Cellular Component
  • Nuclear Envelope Lumen
  • Endoplasmic Reticulum Membrane
  • Membrane
  • Integral Component Of Membrane
  • Perinuclear Region Of Cytoplasm
Molecular Function
  • Glutathione Transferase Activity
  • Glutathione Peroxidase Activity
  • Prostaglandin-D Synthase Activity
  • Protein Binding
  • Glutathione Binding
  • Prostaglandin-E Synthase Activity
Biological Process
  • Prostaglandin Biosynthetic Process
  • Acute Inflammatory Response
  • Chronic Inflammatory Response
  • Prostaglandin Metabolic Process
  • Signal Transduction
  • Negative Regulation Of Cell Population Proliferation
  • Response To Organic Cyclic Compound
  • Sensory Perception Of Pain
  • Cyclooxygenase Pathway
  • Regulation Of Fever Generation
  • Positive Regulation Of Prostaglandin Secretion
  • Response To Lipopolysaccharide
  • Response To Retinoic Acid
  • Response To Cytokine
  • Regulation Of Inflammatory Response
  • Response To Calcium Ion
  • Cellular Oxidant Detoxification
Pathways
  • Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs
Diseases
GWAS
  • Asthma ( 27611488)
  • Pars orbitalis volume ( 31530798)
Interacting Genes 18 interacting genes: BET1 C4orf3 EHHADH GIMAP1 GIMAP5 PLP2 PTGER1 PTGER2 SEC22A SERP2 SMCO4 TMEM19 TMEM222 TMEM65 VAMP3 VAMP4 VAPB YIF1A
Entrez ID 9536
HPRD ID 05528
Ensembl ID ENSG00000148344
Uniprot IDs O14684
PDB IDs 3DWW 4AL0 4AL1 4BPM 4WAB 4YK5 4YL0 4YL1 4YL3 5BQG 5BQH 5BQI 5K0I 5T36 5T37 5TL9
Enriched GO Terms of Interacting Partners?
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