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TPTE2

Description transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
Image No pdb structure
GO Annotations Cellular Component
  • Golgi Membrane
  • Nucleus
  • Endoplasmic Reticulum Membrane
  • Cytosol
  • Plasma Membrane
  • Integral Component Of Membrane
  • Cell Projection
Molecular Function
  • Protein Tyrosine Phosphatase Activity
  • Protein Tyrosine/serine/threonine Phosphatase Activity
  • Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity
Biological Process
  • Protein Dephosphorylation
  • Phosphatidylinositol Biosynthetic Process
  • Negative Regulation Of Cell Population Proliferation
  • Phosphatidylinositol 3-kinase Signaling
  • Dephosphorylation
  • Peptidyl-tyrosine Dephosphorylation
  • Phosphatidylinositol Dephosphorylation
  • Cell Motility
  • Regulation Of Protein Kinase B Signaling
Pathways
  • Synthesis of PIPs at the Golgi membrane
Drugs
Diseases
GWAS
  • Liver fibrosis (total hepatic collagen content) ( 32953199)
Interacting Genes 5 interacting genes: AATK BRCA1 EPHA2 LMTK2 PTK7
Entrez ID 93492
HPRD ID 06003
Ensembl ID ENSG00000132958
Uniprot IDs Q6XPS3
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025